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Items in Final Fantasy VII Rebirth include recovery and offensive items that can be obtained from boxes, treasure chests, item drops, and as quest rewards. During battle, items require one ATB charge. Holding 
on the field, the menu does not close after using an item, allowing the use of multiple items at once. This makes healing the party with potions easier.
As in Final Fantasy VII Remake, items cannot be used in hard mode. 
Item Master Materia improves the efficacy of items used by the character, up to +50% greater than their usual effect.
Recovery items[]
| Item | Description | Drop | Find |
|---|---|---|---|
| Potion | Restores 350 HP to one party member | Shop: All shops (50 gil) | |
| Hi-Potion | Restores 700 HP to one party member | Shop: All shops (300 gil) | |
| Mixed Potion | Restores 350 HP and 20 MP to one party member | Shop: All shops (550 gil) | |
| Mixed Hi-Potion | Restores 700 HP and 20 MP to one party member | ||
| Mist Potion | Restores 350 HP to all party allies | Shop: All shops (150 gil) | |
| Mist Hi-Potion | Restores 700 HP to all party allies | ||
| Mega-Potion | Restores 1,500 HP to one party member | ||
| Giga-Potion | Restores 3,000 HP to one party member | ||
| X-Potion | Fully restores HP to one party member |