Death Machine may refer to:
- An enemy from the original Final Fantasy.
- An enemy from Final Fantasy IV.
- An enemy from Final Fantasy IV: The After Years.
- An enemy from Final Fantasy VI.
- An enemy from Final Fantasy VII.
- An enemy from Crisis Core -Final Fantasy VII-.
- A boss from Final Fantasy Crystal Chronicles: Echoes of Time.
- An enemy from Final Fantasy Crystal Chronicles: The Crystal Bearers.
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