Bubble appears in the 3D versions and is accessible either through Tellah's Recall ability, and through Twincast when Kain is paired up with either Cecil or Rosa. The spell grants the Bubble status on the entire party. It costs 50 MP to use, deducting MP from both users of the Twincast command. The spell is classified as a White Magic spell.
Bubbles is a weak attack that targets all party members, and is used by Clipper.
In the original release, Bubble is an Arcane Magick and the License for the spell is Arcane Magick 5 and costs 60 LP to purchase. The spell can be bought from the Muthru Bazaar after attaining a Clan Rank of Ward of Justice and inside the skyferries between Rabanastre and Nalbina for 3,300 gil after obtaining the Treaty-Blade.
In the Zodiac versions, Bubble is instead a Green Magick spell unlocked with the Green Magick 3 License. Only the four mage jobs, White Mage, Black Mage, Red Battlemage, Time Battlemage, can cast it, as well as Larsa when he joins in Jahara. It can be bought from the Muthru Bazaar after attaining a Clan Rank of Riskbreaker (16 Marks killed).
The Bubble Belt accessory bestows Bubble on its wearer.
Bubble can also be cast via the Euclid's Sextant measure. It is a unique weapon in that if the Bubble status takes effect on the target, the target will not receive any damage.
The Bubble Mote can also be used to cast Bubble. It can be stolen in Trial Mode stage 5 from Nekhbet. Several chests can contain a Bubble mote, including one in the room where Mateus is fought. It can also be bought from the Clan Centurio clan provisioner once the player has reached the Order of Ambrosia rank, achieved by completing the Sky Pirate's Den.
Bubble can be used by all four mage jobs; Cleanse by White Mage, Red Battlemage and Knight. It can be obtained earlier; from the Clan shop after 16 Hunts. And it not only removes but protects against Disease. The only reason to use Cleanse, with the White and Red mages that can have both, is that it costs 20 MP to cast instead of Bubble's 32.