Template:FFXI Spell Bio II is an enhanced version of the original Bio spell in Final Fantasy XI. It deals gradual Dark damage and weakens the afflicted target's physical attacks. The rate of damage, the duration, and the attack stat reduction are all improved over the original Bio spell. The Bio status can be cured with Erase, Esuna, Exuviation, or numerous items, but not by Poisona or Antidotes.
Bio II will overwrite the effects of Dia and Dia II, but can be overwritten by Dia III. The scroll which teaches Bio II can be bought in Selbina, Windurst Waters, and Aht Urhgan Whitegate, or obtained from other players via the Auction House or Bazaars.