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Poison and deal a small amount of non-elemental damage. Guaranteed to hit


Bio is a magic spell in Final Fantasy VII Remake and "Episode INTERmission". It is granted by the Poison Materia Poison Materia. Bio inflicts a small amount of non-elemental damage and the Poison Poison status to one enemy, and can never miss.


Magic Materia Magic Materia Poison Materia Poison Materia
Effects Inflicts Poison Poison on target for 180 seconds
Small non-elemental magic damage
.9 meter area-of-effect
No charge time
Interrupt stats Interrupts targets with <50 interrupt defense
Interrupted by attacks with ≥40 interrupt strength
Compatible Support Materia Support Materia Magnify Materia Magnify Materia
Synergy Materia Synergy Materia
HP Absorption Materia HP Absorption Materia
MP Absorption Materia MP Absorption Materia
Unconditional weapon passive bonuses Debuff Extension
MP Saver: Attack Spells
Special Interrupt(s) None

Damage formula:

Stagger formula:

Where 2 is used rather than 1 while the target is Pressured, and "Target's Magic Modifier" is the target's respective stagger rate modifier.


Bio can be used with the poison materia equipped. Bio can be useful against enemies that resist elements but not magical damage itself, and to poison enemies to inflict passive damage over time. However, many of the party already have abilities that deal non-elemental magical damage without needing to spend MP, like Cloud's Blade Burst or Aerith's normal attacks and various abilities. Bio line of spells are guaranteed to hit, however, making them easy to use.

When paired with Synergy Materia Synergy Materia, the synergizing character can safely use the spell against any opponent as Bio spells deal non-elemental damage; the only time this pairing is useless is when the enemy resists magic damage altogether. Synergy materia is especially useful in Final Fantasy VII Remake Intergrade where the spells cast with it are "free".