Final Fantasy Wiki

Poison element attack


Bio is an attack magic spell in Final Fantasy VII. It is granted by the Poison Materia at level one, and is the basic Poison-elemental spell below Bio2 and Bio3. Bio also has 48% of inflicting the Poison status effect.


Magic Materia Poison, Master Magic
Effect Small poison-elemental damage
48% chance of inflicting Poison
Compatible Support Materia Added Cut
Final Attack
HP Absorb
Magic Counter
MP Absorb
MP Turbo
Quadra Magic
Sneak Attack
Steal as well

Damage formula:

where "Level" is the caster's current level and "Magical Attack" is their Magic atk stat. This is effectively 0.625x the base magic damage.


Bio can be used by characters with the Poison Materia at level 1. Though it has double the MP cost of the equivalent Fire, Ice, and Bolt spells, it deals higher damage, and has a 48% change to inflict the Poison status effect. This status deals physical Poison-elemental damage equivalent to 1/32 of the target's max HP every 2.5 units of time, ignoring the Defense stat and Barrier statuses.

Bio is best cast against enemies weak to Poison-elemental damage, as due to its MP cost, it is not too economical to use frequently against most enemies. However, when cast on larger enemies and bosses, if they are not immune to the Poison status, the damage over time can be particularly helpful for long-lasting battles.

Bio can be amplified by pairing the Poison Materia with Support Materia. All Materia allows it to hit all enemies, and potentially poison multiple enemies at once. Though MP Turbo increases its damage, it is not economical to use compared with using the Materia to boost other spells.

At later levels, Bio becomes outclassed in damage by Bio2 and Bio3. Bio3 has a higher chance of inflicting the Poison status, though if the goal is to inflict Poison rather than to deal Poison damage, it is best to continue using the base Bio spell to conserve MP. Otherwise, if the goal is to take advantage of a vulnerability to the Poison element, using the higher elemental spells is better.

The only enemy with Bio equipped is Lost Number's magical form.