Permanently missable content

A permanently missable item is an item that can be obtained at one point of the game, but can disappear permanently if not acquired soon enough.

Final Fantasy II
The Blood Sword from Josef's house can be permanently missed if the player doesn't go there after learning the key term 'Cyclone' from Hilda.

Final Fantasy V
The elemental rods that can be bought during the duration of the first world can be lost forever if the player does not buy them before moving on to the second world.

Final Fantasy VII
The items obtained as part of Cloud's crossdressing sidequest will be missed if the player does not obtain them during the quest. As there are different versions of each piece of apparel, and the player can only get one item, all items can never be retrieved in a single playthrough. The Silk Dress, Blonde Wig, Sexy Cologne, and Diamond Tiara is the best combination and therefore seen as the required combination for a perfect game.

Some items can only be obtained from one enemy in the game, and once that enemy becomes unavailable, the items can never be retrieved. Such item is the Ghost Hand obtained only from the Ghosts in Train Graveyard. Another such known item is the Vagyrisk Claw, which can only be stolen from the Bagrisk. However, due to the way the way game's steal mechanism works, it will eventually become impossible to steal the Vagyrisk Claw if the player advances too far in character levels.

Some armor can only be obtained one way, and if missed, can never be obtained after. The Aegis Armlet can only be obtained from the Midgar underground in disc 2, the Iron Bangle can only be bought in Sector 7, the Shinra Alpha and Shinra Beta can only be stolen from certain Shinra troops that are not recurring random encounters, the Warrior Bangle can only be stolen from Eagle Gun and the Ziedrich can only be stolen from Turks:Rude.

Some weapons can also be missed. The Enhance Sword can only be found in Gaea's Cliff, Yoshiyuki can only be obtained before the rocket takes off in Rocket Town, the Pile Panger, HP Shout, Master Fist, Grow Lance and Behemoth Horn can only be found in Shinra Headquarters in disc 2, Max Ray and Missing Score can only be found in Midgar in disc 2, and Missing Score only when Barret is in the party, the Umbrella can only be obtained from the rollercoaster game in Gold Saucer in disc 1 and the Princess Guard can only be found in Temple of the Ancients, the Rising Sun can only be stolen from the Diamond Weapon, the Battle Trumpet and Scimitar can only be found in Junon submarine docks and the Starlight M-Phone can only be found in Midgar Underground, the Javelin can only be found in Gaea's Cliff.

Some items found only in unrevisitable locations can never be obtained if missed, such as the Leviathan Scales.

The Huge Materia can be missed if the player fails the quests on which to retrieve them. If the player loses the Fort Condor quest for Huge Materia by losing the boss fight, they lose both the Huge Materia and the Phoenix Materia, although Phoenix can be dug up from Bone Village if missed, so it is not permanently missable. If the player fails to catch up with the train in Mt. Corel they lose the Huge Materia, and if they fail to destroy the red submarine during the submarine minigame, this Huge Materia is lost as well. Lastly, if the player fails to solve the password in the Shinra No. 26 rocket, they cannot retrieve the Huge Materia. Even if the Huge Materia were lost, Bahamut ZERO can still be obtained by digging in the Bone Village.

Final Fantasy VIII
Only two Pet Name Tags are available in the game, from D-District Prison and from a person in Timber (only if the player encourages the man outside Timber Maniacs building). If these two chances are missed, Pet Name Tag cannot be obtained.

The Battle Meter that keeps track of the number of battles the player has fought is missed if the player does not talk to Cid right after graduating into a SeeD. The Character Report, which keeps track of characters' individual battle statistics, is missed if the player does not have Battle Meter first, and if they miss it in D-District Prison. Lastly, the GF Report is missed if the player missed out on the Battle Meter, and fails to obtain it from CC Joker in Balamb Garden training center before disc 3 end.

The Occult Fan volumes III and IV never appear in shops even late in game, so if the player misses the chances of getting them, they will be missed forever.

If the player has the Chocobo World minigame, no items are technically missable, as any items can be obtained from the Chocobo World, even items that are normally one-time-only items, like the Magic Lamp. Some items are also Chocobo World exclusive, namely the Chocobo Tag, Friendship, Ribbon and Moogle Amulet.

Final Fantasy IX
Hippaul can be raced in Alexandria at the beginning of disc 3 for a rather short time only; after the player agrees to see Ruby's play the chance to play the racing minigame ends, meaning the player misses out on the Athlete Queen trophy.

The Namingway card can be missed. One is in Kuja's room in the Desert Palace (near the teleporter, only after Eiko has been kidnapped). The other is in Treno, during the card tournament. When the player is in control of Vivi, they are given the option of "going home", or staying in Treno. Choosing the latter will give Zidane a different opponent in the card tournament's second round, who holds the Namingway card.

Leaving Treno during the card tournament and traveling to Dali is the only time the player can get the Mayor's Key, the Burman Coffee and the Mini-Brahne items. Completing the Morrid's Coffee sidequest lets the player get the mini Prima Vista in the Tantalus hideout in Lindblum, which can likewise be missed if the player fails to get all the different coffee beans.

Excalibur II, Steiner's ultimate weapon, can only be obtained if the player reaches an area in Memoria in under 12 hours playtime. This item is usually always missed, unless the player specifically attempts a speed playthrough of the game. However, since the PAL version runs slightly slower than the NTSC version, it is generally considered impossible to get. It is also considered impossible in the PSN version as the player cannot skip cutscenes by opening the disk tray. The player has more than one opportunity if they let the game clock overflow, however this requires over two years of game time.

Some items may look missable but aren't. If the player finds cards from the world map treasure chests with Choco while their card quota is full, the cards are discarded. However, these cards can still be obtained from the Fat Chocobo in Chocobo's Paradise at the end of the quest.

If the player carries out the Gold Chocobo Bug they miss out on the items in the locations they didn't get to visit.

Final Fantasy X
A number of equipment can be missed in this game that cannot be customized. When the player first enters the Calm Lands, a one-time shop will approach the player, Rin's Traveling Hovercraft. From Rin the player can buy a Buckler for Tidus. Despite its name, it does not just have one empty ability slot, but that slot has Magic Counter equipped to it, and is the only armor in the game that has it equipped. The player can get a weapon with the No Encounters ability for defeating Geosgaeno, and there is no other way to get one. Since there is only a 50% chance of getting a weapon drop, the player can miss this. In the PAL and International versions of the game, they player can in a unique weapon from Penance. Penance drops a weapon with the Break Damage Limit, however unseen by visual means, it will also have a Critical Bonus of 10%. Since there is a 50% chance of obtaining a weapon from the boss, this is missable. Obtaining these three equipment is often considered requirements for a "perfect game".

Final Fantasy XII
The Genji Equipment from the elite mark Gilgamesh can be missed if the player did not steal them during both battles with him. The [Zodiark Spear] can be missed if the player opens any of the 12 chests in the Phon Coast, as they are linked to other chests later in the game.

Final Fantasy XIII
One of the three Doctor's Codes items can be missed if the player never obtains it in the Sunleth Waterscape. An unbuyable Elixer can be missed in the final dungeon if the player decides not to backtrack after the third pre-final boss fight.